ABSTRACT
Enhancing national biodefense science and technology capacity is the basis of and key to biosafety and biosecurity .A further improved biodefense capability is required for the military to defend national sovereignty and territorial integrity , safeguard national interests overseas , and carry out military operations other than war .Currently , global biodefense technology is progressing rapidly .Research on detection and diagnosis products for biological threats focuses on novel, fast, portable, and remote identification technologies .As for biodefense vaccine development , research of vaccines for emerging viruses, bacteria, toxins, and malaria has made positive progress .In biodefense pharmaceutical research , new anti-influenza drugs , anti-Ebola drugs , anti-Marburg virus drugs , and new antibiotics for anthrax and plague keep emerging.In the future, China should give priority to research on biosurveillance and early warning , biodefense product transformation, and all-spectrum biodefense system construction .
ABSTRACT
Though increasing attention is paid to the disruptive technology due to its characteristic, there are so many flaws with the mainstream identification methods for disruptive technology and there is no consensus among experts.By com-bining the findings of the research institutions both at home and abroad and their identification methods,and using such methods as literature and specialist consultation,the types of identification methods,differences in the research institutions of disruptive technology, future development direction and problems of the identification methods are analyzed.Some suggestions on the research of disruptive technology in China are raised for the next step.
ABSTRACT
<p><b>OBJECTIVE</b>In order to explore the existence of SARS coronavirus (Co-V) and/or its RNA in sewage of hospitals administered SARS patients.</p><p><b>METHODS</b>A novel electropositive filter was used to concentrate the SARS-CoV from the sewage of two hospitals administered SARS patients in Beijing, including twelve 2,500 ml sewage samples from the hospitals before disinfection, and ten 25,000 ml samples after disinfection; as well as cell culture, RT-PCR and sequencing of gene to detect and identify the viruses from sewage.</p><p><b>RESULTS</b>There was no live SARS-CoV detected in the sewage in this study. The nucleic acid of SARS-CoV had been found in the 12 sewage samples before disinfection from both hospitals by semi-nested PCR. After disinfection, SARS-CoV RNA could only be detected from the samples from the 309th Hospital, and the others were negative.</p><p><b>CONCLUSION</b>It provides evidence that there is no live SARS-Cov in the sewage from hospitals with SARS patients though SARS-CoV RNA can be detected.</p>